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BreastTrue High Risk Panel (Test Code 8008)

Collection Method

Buccal Swab

Turn Around Time

18-20 business days

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The BreastTrue High Risk Panel is best suited for individuals with either a history of early onset breast or ovarian cancer or a strong family history of breast and/or ovarian cancer. Individuals with the following medical or family history factors should consider testing:

  • Early onset breast cancer (under 50 years of age)
  • Bilateral or multiple breast cancers
  • Diagnosed with both breast and ovarian cancer
  • Family history of breast and/or ovarian cancer

BreastTrue High Risk Panel is a next-generation sequencing test that detects mutations in eight high-risk breast cancer susceptibility genes, including BRCA1, BRCA2 and PALB2. In addition, the test includes deletion/duplication analysis of the BRCA1/2 genes by MLPA.

Recent studies of breast cancer survivors have shown that approximately 70 percent of the mutations identified were BRCA1/2 mutations. Approximately 4 percent had germline mutations in other cancer-susceptibility genes, including high-risk genes. These additional high-risk genes include CDH1, CHEK2, PALB2, PTEN, STK11, and TP53.

 

Test Method

Next Generation Sequencing (NGS)

Analytes

BRCA1, BRCA2, CDH1, PALB2, PTEN, TP53, STK11

Notice To Patients

NutriPATH practices in the usual practitioner-referral system for pathology laboratories.Patients are highly recommended to seek the supervision and guidance of a qualified healthcare practitioner for the interpretation of any lab results and associated information. NutriPATH can offer assistance in locating a suitable practitioner

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NUTRIPATH offers more tests than any other integrative medical laboratory. With more than 200 tests available, it is the anti-aging and integrative medical practitioners’ one-stop-shop with assessments that investigate endocrine, gastrointestinal, immunological, genomic, metabolic and nutritional balance.