450564723

Liver Detoxification Profile- (Test Code 4010)

The process of detoxification is one of the chief roles of the liver. It works to convert lipid-soluble xenobiotics into water soluble substances that can be excreted from the body. It does this via a two-step process designated phase I and phase II. When the function of the liver is sub-optimal, toxins can build up and poison the body. The liver detoxification profile evaluates the ability of an individual to process caffeine, aspirin (salicylate) and paracetamol (acetaminophen) by assessing certain metabolites in salivary and urinary specimens.

Analytes:

Phase I: Caffeine Clearance; Phase 2: Acetaminophen glucuronide (glucuronidation), Salicyluric acid (glycination), Acetaminophen mercapturate (glutathionation), Acetaminophen sulphate (sulphation).

Product Description

450564723

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Turnaround Time:10-15 business days

Patient Brochure

This test is unlike standard liver function tests which only provide a measure of hepatic damage (released hepatic enzyme levels). In contrast, the liver detoxification test is a true functional test as it evaluates the ability of an individual to process caffeine, aspirin (salicylate) and paracetamol (acetaminophen) by assessing certain metabolites in salivary and urinary specimens. Specific measurements of the different phases of liver detoxification including phase I and phase II (glycination, glucuronidation, sulphation and glutathionation) are obtained, guiding the design of effective and specific therapeutic strategies which can optimise liver function.

Common Conditions:

  • Autism
  • Chronic fatigue
  • Food intolerances
  • Headaches
  • Multiple chemical sensitivities
  • Hormonal imbalances
  • Multiple drug therapy

 

 

NOTICE TO PATIENTS

NutriPATH practices in the usual practitioner-referral system for pathology laboratories. Patients are highly recommended to seek the supervision and guidance of a qualified healthcare practitioner for the interpretation of any lab results and associated information. NutriPATH can offer assistance in locating a suitable practitioner.

 

Analytes

Phase I: Caffeine Clearance; Phase 2:
Acetaminophen glucuronide (glucuronidation)
Salicyluric acid (glycination)
Acetaminophen mercapturate (glutathionation)
Acetaminophen sulphate (sulphation)