56459125

Porphyrins-Spot Urine (Test Code 4024)

Porphyrins are intermediate products in the production of haem which involves at least eight enzymes which are highly sensitive to toxins. Secondary porphyrias (porphyrinurias) are defined as porphyrias that occur without a genetic defect of haem synthesis.  These porphyrias are associated with environmental exposure to toxins and it has been hypothesised that several health disorders have abnormal porphyrin levels associated with chemical exposure.  These conditions include chronic fatigue, multiple chemical sensitivities, learning and behavioural disorders as well as mental conditions.

Analytes:

Uroporphyrins I, Uroporphyrins III, 7-Carboxy Porphyrin, 6-Carboxy Porphyrin, 5-Carboxy Porphyrin, Precoproporphyrins, Coproporphyrins I, Coproporphyrins III.

Product Description

56459125

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Patient Brochure

The porphyrin test is a powerful biomarker of environmental toxicity.  Porphyrins are intermediate products in the production of haem which involves at least eight enzymes which are highly sensitive to toxins.  When certain chemicals are present in the body these enzymes are inhibited, particular porphyrins build up and a distinctive pattern of porphyrins specific to each toxin is produced.  These patterns of porphyrin production can therefore be used to analyse the presence of environmental toxins in the body and therefore of chemical exposure.  Common toxins which affect porphyrin metabolism include lead, mercury, arsenic, cadmium, hexachlorobenzene and dioxins.

Several health disorders have abnormal porphyrin levels associated with chemical exposure including chronic fatigue, multiple chemical sensitivities, learning and behavioural disorders, as well as mental health conditions.  Multiple studies have recently revealed that autism spectrum disorder (ASD) is also associated with abnormal patterns of porphyrin production.  It was suggested that porphyrins should be routinely measured in ASD and potential ASD treatments should consider monitoring porphyrin levels.

Common Conditions:

  • Autism
  • Allergies
  • Multiple chemical sensitivities
  • Chronic Fatigue Syndrome
  • Mental health

 

NOTICE TO PATIENTS

NutriPATH practices in the usual practitioner-referral system for pathology laboratories. Patients are highly recommended to seek the supervision and guidance of a qualified healthcare practitioner for the interpretation of any lab results and associated information. NutriPATH can offer assistance in locating a suitable practitioner.

 

Analytes

Uroporphyrins I
Uroporphyrins III
7-Carboxy Porphyrin
6-Carboxy Porphyrin
5-Carboxy Porphyrin
Precoproporphyrins
Coproporphyrins I
Coproporphyrins III