Collection Instructions


Collection Method


Kit Requirements

4 x 5ml Saliva

Turn Around Time

3-5 Business Days Turnaround times are estimates


Sample Report


The Adrenocortex hormone profile is a non-invasive saliva test that serves as a reliable marker of stress response and a critical tool for revealing adrenal imbalances. Lifestyle, physical and psychological stresses put constant demands on the adrenal glands. If they become depleted adrenal fatigue or insufficiency may be experienced.

Each person has two adrenal glands both located on top of each of the body’s two kidneys. These glands are important to the body’s endocrine (hormonal) system. Adrenal fatigue is a very common condition in today’s society through the physical and physiological demands we put on our adrenal glands. Each gland is composed of two distinct zones, the large outer cortex and the inner medulla.

The Adrenocortex stress profile extensive is an expansion of the Adrenocortex basic test in the sense that it includes Secretory IgA levels. Salivary cortisol testing is an effective non-invasive salivary hormone test that evaluates bioactive levels of the body’s important stress hormones, cortisol and DHEA. This hormone test (stress test) serves as a critical tool for uncovering biochemical imbalances underlying anxiety, depression, chronic fatigue syndrome, obesity, dysglycemia, and a host of other clinical conditions that may affect our day to day lives. This hormone test examines 4 saliva samples over a 12-hour period for levels of cortisol DHEA and Secretory IgA. The Adrenocortex extensive test is a very useful tool for patients that have weak immune systems and susceptible to always catching the flu.


Tsigos C, Chrousos GP. Hypothalamic-pituitary-adrenal axis, neuroendocrine factors and stress. Journal of psychosomatic research. 2002;53(4):865-871.

Fries E, Dettenborn L, Kirschbaum C. The cortisol awakening response (CAR): facts and future directions. IntJPsychophysiol. 2009;72(1):67-73.

Clow A, Hucklebridge F, Stalder T, Evans P, Thorn L. The cortisol awakening response: more than a measure of HPA axis function. NeurosciBiobehavRev. 2010;35(1):97-103.

Hackett RA, Kivimäki M, Kumari M, Steptoe A. Diurnal Cortisol Patterns, Future Diabetes, and Impaired Glucose Metabolism in the Whitehall II Cohort Study. The Journal of Clinical Endocrinology & Metabolism. 2016;101(2):619-625.

Hammer F, Deutschbein T, Marx A, et al. High evening salivary cortisol is an independent predictor of increased mortality risk in patients with systolic heart failure. International journal of cardiology. 2016;203:69-73.

Engeland CG, Hugo FN, Hilgert JB, et al. Psychological distress and salivary secretory immunity. Brain Behav Immun. 2016;52:11‐17. doi:10.1016/j.bbi.2015.08.017

Amir H Abdul Latiff and Michael A Kerr – The clinical significance of immunoglobulin A deficiency. Ann Clin Biochem, Mar 2007; 44: 131 – 139.


  • Cortisol 12:00pm
  • Cortisol 4:00pm
  • Cortisol 6:00-8:00am
  • Cortisol 8:00pm
  • DHEAs 6:00-8:00am
  • Secretory IgA

Test Method

EIA (Enzyme immunoassay)

Common Conditions

  • Nutritional and Dietary Symptoms
    • Bone loss
    • Weight gain
  • Mental and Emotional Health
    • Brain fog
    • Depression
  • Other Health Conditions
    • Disturbed sleep patterns
    • Fatigue
    • Hot flushes
    • Insomnia
    • Irregular menstruation
    • Low libido
    • Miscarriage
    • Mood changes
    • Night sweats
    • PCOS
    • PMS
  • Skin and Dermatological Health
    • Dry skin
  • Reproductive Health
    • Infertility
    • Vaginal dryness
  • Endocrine and Hormonal Health
    • Symptoms of menopause

Notice To Patients

NutriPATH practices in the usual practitioner-referral system for pathology laboratories. Patients are highly recommended to seek the supervision and guidance of a qualified healthcare practitioner for the interpretation of any lab results and associated information. NutriPATH can offer assistance in locating a suitable practitioner.

Find a Practitioner

How it works

Step 1

Order test

Your referring practitioner will place this order via their online portal.

Step 2

Collect Samples

A test kit will be dispatched to you and you can conveniently collect your sample in the comfort of your home.

Step 3

Return Samples

Return samples for analysis via the provided courier packaging.

Patient resources

Our highly skilled and qualified team have created a service where patients can easily gain access to a wide range of pathology testing options.

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Practitioner resources

As a leader in the industry, practitioners are able to trust in our ability to provide them with the technology they need to adequately test their clients and patients.

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