Collection Method


Kit Requirements


Turn Around Time

21 business days Turnaround times are estimates


Sample Report


Apolipoprotein E short for APO-E is produced primarily in the liver and brain which has two primary distinct roles:

  1. The transport of lipids from where they are made or absorbed to the tissues where they are stored.
  2. The transport of cholesterol and other lipids from the body’s organs to the liver for excretion.

The APOE gene exists in three different forms (alleles) – e2, e3, and e4 – with e3 being the most common allele, found in 60 per cent of the general population. Everyone inherits two APOE genes, one from each parent that is some combination of these three forms.

Recent studies have shown that the APO E gene test is a useful diagnostic test to help confirm a diagnosis of Type III hyperlipoproteinaemia and a diagnosis of late onset Alzheimer’s disease (AD) in a symptomatic adult.

Why get tested?

  • If you have elevated cholesterol and triglyceride levels that do not respond to lifestyle changes.
  • If you suspect Alzheimer’s disease
  • If you have a family history of heart disease



Corder EH, Saunders AM, Strittmatter WJ, et al. Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer’s disease in late onset families. Science. 1993;261(5123):921‐923. doi:10.1126/science.8346443

Marais AD. Apolipoprotein E in lipoprotein metabolism, health and cardiovascular disease. Pathology. 2019;51(2):165-176. doi:10.1016/j.pathol.2018.11.002


  • APO E- (alleles)
    • e2
    • e3
    • e4

Test Method

PCR genotyping

Notice To Patients

NutriPATH practices in the usual practitioner-referral system for pathology laboratories. Patients are highly recommended to seek the supervision and guidance of a qualified healthcare practitioner for the interpretation of any lab results and associated information. NutriPATH can offer assistance in locating a suitable practitioner.

Find a Practitioner

How it works

Step 1

Order test

Your referring practitioner will place this order via their online portal.

Step 2

Collect Samples

A test kit will be dispatched to you and you can conveniently collect your sample in the comfort of your home.

Step 3

Return Samples

Return samples for analysis via the provided courier packaging.

Patient resources

Our highly skilled and qualified team have created a service where patients can easily gain access to a wide range of pathology testing options.

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Practitioner resources

As a leader in the industry, practitioners are able to trust in our ability to provide them with the technology they need to adequately test their clients and patients.

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