Elevated homocysteine is known to increase the risk of cardiovascular disease mortality, coronary artery disease, chronic heart failure and cerebrovascular and peripheral vascular disease. Its involvement in these conditions may be related to its prothrombotic properties, proliferative effect on smooth muscle cells and pro-oxidant activity.
Homocysteine, a sulphur-containing amino acid is an intermediate product in the normal biosynthesis of the amino acids methionine and cysteine. Homocysteine is predominantly metabolised via two pathways. The enzyme MTHFR converts homocysteine to methionine. The MTHFR is strongly dependent on cofactors folate and vitamin B12.
In addition, homocysteine can increase coagulability, cause endothelial dysfunction, induce the production of inflammatory factors and accelerate atherosclerosis in animal models. High levels are also associated with stroke, cognitive deficit, autism, Alzheimer’s disease, bone fracture, osteoporosis and depression. The role of homocysteine in these disorders may also be related to its pro-oxidant activity, the induction of pro-inflammatory factors and its negative affects on blood vessels.
- Other Health Conditions
- Alzheimer’s disease
- Mental and Emotional Health
- Cognitive deficit
- Cardiovascular Health
- Cardiovascular Disease
- Neurological Symptoms
Notice To Patients
NutriPATH practices in the usual practitioner-referral system for pathology laboratories. Patients are highly recommended to seek the supervision and guidance of a qualified healthcare practitioner for the interpretation of any lab results and associated information. NutriPATH can offer assistance in locating a suitable practitioner.
How it works
Your referring practitioner will place this order via their online portal.
A test kit will be dispatched to you and you can conveniently collect your sample in the comfort of your home.
Return samples for analysis via the provided courier packaging.
Our highly skilled and qualified team have created a service where patients can easily gain access to a wide range of pathology testing options.
As a leader in the industry, practitioners are able to trust in our ability to provide them with the technology they need to adequately test their clients and patients.