Collection Instructions


Collection Method


Kit Requirements

Stool Test Kit

Turn Around Time

3-5 Business Days Turnaround times are estimates


Sample Report


M2 Pyruvate Kinase (M2-PK), as measured in faeces, is a tumour marker for colorectal cancer.  Though M2-PK can be elevated in many tumour types, rather than being an organ-specific tumour marker, increased stool (faecal) levels can be used as a early detection of colorectal carcinomas.

The detection of M2-PK does not depend on blood in the stool and is specifically related to changes in tumour metabolism. The M2-PK test is a non-invasive stool test that can be used for the early detection of colorectal cancers and polyps which are known to be the precursors of colorectal cancer.

Increased M2-PK values can sometimes also occur in severe inflammatory diseases which must be excluded by differential diagnosis. If elevated levels of M2PK are present, it is recommended to request more specific tumour marker tests such as (CEA) for bowel cancer, CA 19-9 for pancreatic cancer and CA 72-4 for gastric cancer. This will significantly increase the sensitivity to detect various cancers.

M2PK can be ordered as a single marker or in alliance with a CDSA panel that includes certain GIT markers.

Reference:Abdullah M, Rani AA, Simadibrata M, Fauzi A, Syam AF. The value of fecal tumor M2 pyruvate kinase as a diagnostic tool for colorectal cancer screening. Acta Med Indones. 2012;44(2):94‐99.


  • M2 Pyruvate Kinase (M2-PK)

Test Method

EIA (Enzyme immunoassay)

Common Conditions

  • Gastrointestinal and Digestive Health
    • Bloating, pain or nausea
    • Cholecystectomy
    • Gastroesophageal reflux symptoms
    • Loose or watery stools
    • Undigested food in the stool
  • Endocrine and Hormonal Health
    • Diabetes
    • Hypochlorhydria
  • Other Health Conditions
    • Food intolerances
    • Osteoporosis

Notice To Patients

NutriPATH practices in the usual practitioner-referral system for pathology laboratories. Patients are highly recommended to seek the supervision and guidance of a qualified healthcare practitioner for the interpretation of any lab results and associated information. NutriPATH can offer assistance in locating a suitable practitioner.

Find a Practitioner

How it works

Step 1

Order test

Your referring practitioner will place this order via their online portal.

Step 2

Collect Samples

A test kit will be dispatched to you and you can conveniently collect your sample in the comfort of your home.

Step 3

Return Samples

Return samples for analysis via the provided courier packaging.

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