Collection Method

MCAS Collection Kit (Blood & Urine)

Turn Around Time

30 business days Turnaround times are estimates


Sample Report


Mast Cell Activation Syndrome (MCAS) is a condition where a patient may have a normal level of mast cells present, but these cells may be over-responsive or overreact to the body.  Symptoms are usually related to the excess and episodic release of inflammatory mediators from mast cells. A common presentation is recurrent anaphylaxis where no trigger or cause can be identified. It is often a challenging condition to detect because the inflammatory mediators may only be released during an episode, then return to normal levels. For example, if the patient is amidst a flare-up they may or may not have an elevated serum tryptase level.

NutriPATH have three panels available for MCAS assessment.

The MCAS Profile – Basic Code 3409 includes some of the basic inflammatory mediators that may be released in Mast Cell Activation syndrome. For example, these include Tryptase, Chromogranin A, Whole Blood Histamine. Tryptase is a serine protease that is released during mast cell degranulation. Chromogranin A is another inflammatory mediator used to identify MCAS.



  • Code 3409
    • Chromogranin A
    • Tryptase
    • WB Histamine

Test Method

LCMS/MS-Liquid chromatography–mass spectrometry

Automated Chemistry


Common Conditions

  • Other Health Conditions
    • Heart symptoms (low blood pressure, rapid heart rate)
    • Hives
    • Itching (pruritus)
    • Swelling
  • Respiratory Health
    • Shortness of breath
    • Wheezing
  • Skin and Dermatological Health
    • Skin Flushing ie. skin turning red

Notice To Patients

NutriPATH practices in the usual practitioner-referral system for pathology laboratories. Patients are highly recommended to seek the supervision and guidance of a qualified healthcare practitioner for the interpretation of any lab results and associated information. NutriPATH can offer assistance in locating a suitable practitioner.

Find a Practitioner

How it works

Step 1

Order test

Your referring practitioner will place this order via their online portal.

Step 2

Collect Samples

A test kit will be dispatched to you and you can conveniently collect your sample in the comfort of your home.

Step 3

Return Samples

Return samples for analysis via the provided courier packaging.

Patient resources

Our highly skilled and qualified team have created a service where patients can easily gain access to a wide range of pathology testing options.

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Practitioner resources

As a leader in the industry, practitioners are able to trust in our ability to provide them with the technology they need to adequately test their clients and patients.

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