Collection Method
CI05.50.01
Kit Requirements
myDNA Swab (Orange)
Turn Around Time
21-24 Business Days Turnaround times are estimates
Description
myDNA Cardiovascular Profile
Using a straightforward and non-invasive buccal swab, this panel evaluates 175 genes associated with cardiovascular health. Cardiomyopathies encompass both genetically inherited and acquired conditions, with a notable proportion being hereditary diseases contributing significantly to morbidity and mortality.
Cardiomyopathies are categorised into Dilated Cardiomyopathy (DCM), Hypertrophic Cardiomyopathy (HCM), Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC), Restrictive Cardiomyopathy (RCM), and LV Noncompaction (LVNC), as well as secondary cardiomyopathies such as Noonan syndrome (NS). HCM stands out as the most prevalent genetic heart disease, characterised by left ventricular hypertrophy that may lead to heart failure and sudden cardiac death (Yamada & Nomura, 2021).
There are three primary justifications for incorporating genetic testing for cardiomyopathy into clinical practice: it facilitates early diagnosis, it can detect secondary cardiomyopathies, and can help predict prognosis (Kubo & Kitaoka, 2023).
Analytes
- A2ML1
- ABCC9
- ACADVL
- ACTC1
- ACTN2
- AGL
- ALMS1
- ANKRD1
- BAG3
- BRAF
- CACNA1C
- CALR3
- CAV3
- CBL
- CHRM2
- CPT2
- CRYAB
- CSRP3
- CTF1
- CTNNA3
- DES
- DMD
- DNAJC19
- DOLK
- DSC2
- DSG2
- DSP
- DTNA
- ELAC2
- EMD
- EYA4
- FHL1
- FHL2
- FKRP
- FKTN
- FLNC
- GAA
- GATA4
- GATA6
- GATAD1
- GLA
- HCN4
- HRAS
- ILK
- JPH2
- JUP
- KRAS
- LAMA4
- LAMP2
- LDB3
- LMNA
- LRRC10
- MAP2K1
- MAP2K2
- MTO1
- MYBPC3
- MYH6
- MYH7
- MYL2
- MYL3
- MYLK2
- MYOM1
- MYOZ2
- MYPN
- NEBL
- NEXN
- NF1
- NKX2-5
- NPPA
- NRAS
- PDLIM3
- PKP2
- PLEKHM2
- PLN
- PRDM16
- PRKAG2
- PTPN11
- RAF1
- RASA1
- RBM20
- RIT1
- RRAS
- RYR2
- SCN5A
- SDHA
- SGCD
- SHOC2
- SLC22A5
- SOS1
- SOS2
- SPRED1
- TAZ
- TBX20
- TCAP
- TGFB3
- TMEM43
- TMEM70
- TMPO
- TNNC1
- TNNI3
- TNNT2
- TPM1
- TTN
- TTR
- TXNRD2
- VCL
Test Method
Illumina Micro-Array
NGS
Common Conditions
- Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC)
- Dilated Cardiomyopathy (DCM)
- Hypertrophic Cardiomyopathy (HCM)
- LV Noncompaction (LVNC)
- Noonan syndrome (NS)
- Restrictive Cardiomyopathy (RCM)
Notice To Patients
NutriPATH practices in the usual practitioner-referral system for pathology laboratories. Patients are highly recommended to seek the supervision and guidance of a qualified healthcare practitioner for the interpretation of any lab results and associated information. NutriPATH can offer assistance in locating a suitable practitioner.
How it works
Step 1
Order test
Your referring practitioner will place this order via their online portal.
Step 2
Collect Samples
A test kit will be dispatched to you and you can conveniently collect your sample in the comfort of your home.
Step 3
Return Samples
Return samples for analysis via the provided courier packaging.
Patient resources
Our highly skilled and qualified team have created a service where patients can easily gain access to a wide range of pathology testing options.
Practitioner resources
As a leader in the industry, practitioners are able to trust in our ability to provide them with the technology they need to adequately test their clients and patients.
